2024

30. Cellular fate of a plant virus cancer immunotherapy candidate. 
    Omole, A.O., Affonso de Oliveira, J.F., Sutorus, L., Karan, S., Zhao, Z., Neun, B.W., Cedrone, E., Clogston, J.D., Xu, J., Sierk, M., Chen, Q., Meerzaman, D., Dobrovolskaia, M.A., & Steinmetz, N.F. (2024)
    Communications Biology, 7(1), 1382.
31. Virus nanotechnology for intratumoral immunotherapy. 
    Omole, A.O., Zhao, Z., Chang-Liao, S., Affonso de Oliveira, J.F., Boone, C.E., Sutorus, L., Sack, M., Varner, J., Fiering, S., & Steinmetz, N.F. (2024) **Cover Art**
    Nature Reviews Bioengineering, 1-14.
32. Chemically Tagging Cargo for Specific Packaging inside and on the Surface of Virus-Like Particles. 
    Hussain, T., Zhao, Z., Murphy, B., Taylor, Z., Gudorf, J., Barnes, L., Klein, S., VanNieuwenhze, M.S., Jarrold, M.F., & Zlotnick, A. (2024)
    ACS nano 18(32), 21024-21037.
33. Cowpea Mosaic Virus Intratumoral Immunotherapy Maintains Stability and Efficacy after Long-Term Storage. 
    Simms, A., Zhao, Z., Cedrone, E., Dobrovolskaia, M.A., & Steinmetz, N.F. (2024)
    Bioengineering & Translational Medicine, e10693. 
34. Multifaceted Cancer Alleviation by Cowpea Mosaic Virus in a Bioprinted Ovarian Cancer Peritoneal Spheroid Model. 
    Xiang, Y.#, Zhao, Z.#, Yao, E.J., Balayan, A., Fiering, S.N., Steinmetz, N.F., & Chen, S. (2024) #Co-first author 
    Biomaterials, 311, 122663.
35. Guanidine Hydrochloride Induced Hepatitis B Virus Capsid Disassembly Hysteresis. 
    Khaykelson, D., Asor, R., Zhao, Z., Schlicksup, C.J., Zlotnick, A., & Raviv, U. (2024)
    Biochemistry, 63(12), 1543-1522.
36. Combination of cowpea mosaic virus (CPMV) intratumoral therapy and oxaliplatin chemotherapy. 
    Moreno-Gonzalez, M.A., Zhao, Z., Caparco, A.A., & Steinmetz, N.F. (2024)
    Materials Advances, 5(11), 4878-4888.
37. Systemic Administration of Cowpea Mosaic Virus Demonstrates Broad Protection Against Metastatic Cancers. 
    Chung, Y.H., Zhao, Z., Jung, E., Omole, A.O., Wang, H., Sutorus, L., & Steinmetz, N.F. (2024)
    Advanced Science, 11(18), 2308237.
38. Peptide-Driven Proton Sponge Nano-Assembly for Imaging and Triggering Lysosome-Regulated Immunogenic Cancer Cell Death. 
    He, T., Wen J., Wang, W., Hu, Z., Ling, C., Zhao, Z., Cheng, Y., Chang, Y.C., Xu, M., Jin, Z., Amer, L., Sasi, L., Fu, L., Steinmetz, N.F., Rana, T.M., Peng, W., & Jokerst, J.V. (2024)
    Advanced Materials, 36(19), 2307679.
39. 3D Bioprinting Cowpea Mosaic Virus as an Immunotherapy Depot for Ovarian Cancer Prevention in a Preclinical Mouse Model. 
    Zhao, Z.#, Xiang, Y.#, Koellhoffer, E.C., Shukla, S., Fiering, S.N., Chen, S., & Steinmetz, N.F. (2024) #Co-first author 
    Materials Advances, 5(4), 1480-1486.
40. Melanoma immunotherapy enabled by M2 macrophage targeted immunomodulatory cowpea mosaic virus.
    Zhao, Z.#, Chung, Y.H.#, & Steinmetz, N.F. (2024) #Co-first author 
    Materials Advances, 5(4), 1473-1479.

2023

19. A co-delivered vaccine of irradiated cancer cells and cowpea mosaic virus improves ovarian cancer rejection. 
    Zhao, Z., Ortega-Rivera, O. A., Chung, Y.H., Simms, A, & Steinmetz, N.F. (2023)
    Journal of Materials Chemistry B, 11 (24), 5429-5441.
20. Viral Nanoparticle Vaccines Against S100A9 Reduce Lung Metastasis. 
    Chung, Y.H., Ortega-Rivera, O. A., Volckaert, B, Jung, E., Zhao, Z., & Steinmetz, N.F. (2023)
    PNAS, 120(43), e2221859120.
21. Physalis mottle virus-like nanocarriers with expanded internal loading capacity. 
    Barkovich, K.J., Wu, Z., Zhao, Z., Simms, A., Chung, Y.H., & Steinmetz, N.F. (2023)
    Bioconjugate Chemistry, 34(9), 1585-1595.
22. iRGD-targeted Physalis Mottle Virus-like Nanoparticles for Targeted Cancer Delivery. 
    Barkovich, K.J., Zhao, Z., & Steinmetz, N.F. (2023)
    Small Science, 3(8), 2300067.
23. COVID-19 vaccines based on viral nanoparticles displaying a conserved B-cell epitope show potent immunogenicity and a long-lasting antibody response. 
    Affonso de Oliveira, J.F., Zhao, Z., Xiang, Y., Shin, M.D., Villaseñor, K.E., Deng, X., Shukla, S., Chen, S., & Steinmetz, N.F. (2023)
    Frontiers in Microbiology 14, 1117914.

2022

14. Cisplatin-loaded tobacco mosaic virus for ovarian cancer treatment. 
    Zhao, Z., Simms, A, & Steinmetz, N.F. (2022)
    Biomacromolecules, 23 (10), 4379-4387.
15. Tuning the Hydrophilic–Hydrophobic Balance of Molecular Polymer Bottlebrushes Enhances their Tumor Homing Properties. 
    Ramamurthi, P.#, Zhao, Z.#, Burke, E., Steinmetz, N. F., & Müllner, M. (2022) #Co-first author
    Advanced Healthcare Materials, 11(12), 2200163. 
16. Isolation of a peptide that binds to Pseudomonas aeruginosa lytic bacteriophage. 
    Chan, S.K., Zhao, Z., Penziner, S., Khong, E., Pride, D., Schooley, R., & Steinmetz, N.F. (2022)
    ACS Omega, 7 (42), 38053-38060. 

2021

11. Asymmetrizing an icosahedral virus capsid by hierarchical assembly of subunits with designed asymmetry. 
    Zhao, Z., Wang, J.C.Y., Zhang, M., Lyktey, N.A., Jarrold, M.F., Jacobson, S.C. & Zlotnick, A. (2021)
    Nature Communications,12(1), 1-10.

2020

10. The integrity of the intradimer interface of the Hepatitis B Virus capsid protein dimer regulates capsid self-assembly.
    Zhao, Z., Wang, J.C.Y., Segura, C.P., Hadden-Perilla, J.A., & Zlotnick, A. (2020)
    ACS Chemical Biology,15(12), 3124-3132.
11. The unique potency of Cowpea mosaic virus (CPMV) in situ cancer vaccine. 
    Shukla, S., Wang, C., Beiss, V., Cai, H., Washington, T., Murray, A.A., Gong, X., Zhao, Z., Masarapu, H.,   Zlotnick, A., Fiering, S. & Steinmetz, N. (2020)
    Biomaterials Science, 8(19), 5489-5503.
12. Capsid protein dynamics regulate Hepatitis B virus assembly through an allosteric network. 
    Patterson, A., Zhao, Z., Waymire, E., Zlotnick, A., & Bothner, B. (2020)
    ACS Chemical Biology, 15(8), 2273-2280.
13. Rapidly Forming Early Intermediate Structures Dictate the Pathway of Capsid Assembly. 
    Asor, R., Schlicksup, C.J., Zhao, Z., Zlotnick, A., & Raviv, U. (2020)
    Journal of the American Chemical Society, 142(17), 7868-7882.

2019

6. Structural differences between the Woodchuck hepatitis virus core protein in dimer and capsid states are consistent with entropic and conformational regulation of assembly.
   Zhao, Z., Wang, J.C.Y., Gonzalez-Gutierrez, G., Venkatakrishnan, B., Asor, R., Khaykelson, D., Raviv, U. & Zlotnick, A. (2019)
   Journal of virology, 93(14), e00141-19. 
7. Assembly Reactions of Hepatitis B Capsid Protein into Capsid Nanoparticles Follow a Narrow Path through a Complex Reaction Landscape. 
   Asor, R., Selzer, L., Schlicksup, C.J., Zhao, Z., Zlotnick, A., & Raviv, U. (2019)
   ACS nano, 13(7), 7610-7626.

2018

4. Multiple Pathways in Capsid Assembly. 
   Lutomski, C.A., Lyktey, N.A., Pierson, E.E., Zhao, Z., Zlotnick, A., & Jarrold, M.F. (2018)
   Journal of the American Chemical Society, 140(17), 5784-5790. 
5. Virus assembly antagonists from redesigned antibodies. 
   Zhao, Z. and Zlotnick, A. (2018)
   Structure, 26(10), 1297-1299. 
6. Hepatitis B virus capsid completion occurs through error correction. 
   Lutomski, C.A., Lyktey, N.A., Zhao, Z., Pierson, E.E., Zlotnick, A., & Jarrold, M.F. (2017)
   Journal of the American Chemical Society, 139(46), 16932-16938. 

2014

1. A copper-responsive gene cluster is required for copper homeostasis and contributes to oxidative resistance in Deinococcus radiodurans R1. 
   Zhao, Z., Zhou, Z., Li, L., Xian, X., Ke, X., Chen, M., & Zhang, Y. (2014)
   Molecular BioSystems, 10(10), 2607-2616.